Skip to main content
. 2020 Jul 27;47(Suppl 22):4–60. doi: 10.1111/jcpe.13290
Evidence‐based recommendation (2.10)
We recommend not to use systemic or local non‐steroidal anti‐inflammatory drugs (NSAIDs) as an adjunct to subgingival instrumentation
Supporting literature Donos et al. (2019)
Quality of evidence Two placebo‐controlled RCTs (n = 88) on local application (1% flurbiprofen toothpaste; irrigation with 200 ml buffered 0.3% acetylsalicylic acid); two placebo‐controlled RCTs (n = 133) on systemic applications (celecoxib, diclofenac potassium)
Grade of recommendation Grade A—↓↓
Strength of consensus Strong consensus (1.3% of the group abstained due to potential CoI)