Evidence‐based recommendation (2.10) |
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We recommend not to use systemic or local non‐steroidal anti‐inflammatory drugs (NSAIDs) as an adjunct to subgingival instrumentation |
Supporting literature Donos et al. (2019) |
Quality of evidence Two placebo‐controlled RCTs (n = 88) on local application (1% flurbiprofen toothpaste; irrigation with 200 ml buffered 0.3% acetylsalicylic acid); two placebo‐controlled RCTs (n = 133) on systemic applications (celecoxib, diclofenac potassium) |
Grade of recommendation Grade A—↓↓ |
Strength of consensus Strong consensus (1.3% of the group abstained due to potential CoI) |