| Evidence‐based recommendation (2.12) |
|---|
| We recommend not to use local administration of metformin gel as adjunct to subgingival instrumentation. |
| Supporting literature Donos et al. (2019) |
| Quality of evidence Six placebo‐controlled RCTs (n = 313) on locally delivered 1% metformin gel |
| Grade of recommendation Grade A—↓↓ |
| Strength of consensus Strong consensus (0% of the group abstained due to potential CoI) |
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