TABLE 1.
Individuals With TS/CTD (n = 3449) | Unaffected Individuals (n = 6,123,841) | |||
---|---|---|---|---|
n | % | n | % | |
Sex | ||||
Men | 2619 | 75.94 | 3,129,702 | 51.11 |
Women | 830 | 24.06 | 2,994,139 | 48.89 |
Age at start of follow‐up, years a | ||||
18–19 | 2684 | 77.82 | 1,969,426 | 32.16 |
20–29 | 354 | 10.26 | 1,036,797 | 16.93 |
30–39 | 196 | 5.68 | 1,014,092 | 16.56 |
40–49 | 133 | 3.86 | 996,119 | 16.27 |
50–65 | 82 | 2.38 | 1,107,407 | 18.08 |
Psychiatric comorbidities b | ||||
Autism spectrum disorders | 925 | 26.82 | 23,748 | 0.39 |
Attention deficit hyperactivity disorder | 1738 | 50.39 | 73,820 | 1.21 |
Conduct disorder | 177 | 5.13 | 4698 | 0.08 |
Anxiety disorders | 1163 | 33.72 | 345,088 | 5.64 |
Obsessive‐compulsive disorder | 757 | 21.95 | 24,008 | 0.39 |
Posttraumatic and other stress‐related disorders | 407 | 11.80 | 148,408 | 2.42 |
Eating disorders | 81 | 2.35 | 26,593 | 0.43 |
Depression and other mood disorders | 1001 | 29.02 | 292,868 | 4.78 |
Bipolar disorders | 220 | 6.38 | 49,644 | 0.81 |
Schizophrenia and other psychotic disorders | 235 | 6.81 | 50,710 | 0.83 |
Substance use disorders | 585 | 16.96 | 236,462 | 3.86 |
Dissocial personality disorder | 24 | 0.70 | 2426 | 0.04 |
Abbreviations: TS, Tourette syndrome; CTD, chronic tic disorder.
Individuals are followed from their 18th birthday or January 1, 1997, whichever occurred last.
The study participants, both exposed and unexposed, may have more than one psychiatric comorbid disorder.