FIGURE 7.

Overexpression of hypoxia inducible factor (HIF)‐2α alters neural crest gene expression. A‐D, Relative mRNA expression of trunk neural crest specific, A, neural crest, B, cranial neural crest, C, and EPAS1, D, genes in dissected neural tube tissue derived from the trunk axial level of embryos electroporated with pCI‐CTRL or pCI‐EPAS1 for overexpression of HIF‐2α, measured by qRT‐PCR 24 hours postelectroporation. Data presented as mean of n = 2 biologically independent repeats, error bars denote SEM. Statistical significance was determined by two‐sided student's t test