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The induction of HIF‐1α in the pro‐cancer effects of ANXA3 on melanoma. Cell growth (A), cell progression (B and C), cell migration (D and E), LDH activity and caspase‐3/9 activity levels (F‐H), HIF‐1α/VEGF expression (I‐K). Negative, negative group; si‐ANXA3, 50 ng of siANXA3 group; si‐ANXA3 + HIF‐1α, 50 ng of si‐ANXA3 group, and up‐regulation of HIF‐1α. **P < .01 versus negative group, *P < .01 versus 50 ng of ANXA3
