Table 1.
Demographics of MD Patients and Controls
| Demographics | MD patients (n = 37) | Controls (n = 37) | P‐value |
|---|---|---|---|
| Age, y (mean ± SD) | 42 ± 13 | 42 ± 12 | .84 |
| Female (n/%) | 22 (59%) | 22 (59%) | |
| BMI, kg/m b , (median: IQR) | 21.9: 19.9–24.5 | 23.0: 21.3–25.0 | .54 |
| BMI categories (n/%) | |||
| <18.5, kg/m b | 2 (5%) | 0 (0%) | |
| <20, kg/m 2 | 9 (24%) | 4 (11%) | |
| 20–25, kg/m 2 | 20 (54%) | 23 (62%) | |
| 25–30, kg/m 2 | 6 (16%) | 10 (27%) | |
| >30, kg/m 2 | 2 (5%) | 0 (0%) | |
| Weight, kg (mean ± SD) | 66.6 ± 12.3 | 72.2 ± 8.9 | .04 |
| Weight loss a (n/%) | 4 (11%) | 2 (5%) | .39 |
| Height, cm (mean ± SD) | 170.8 ± 1.0 | 176.4 ± 0.9 | .01 |
| Waist circumference, cm, (mean ± SD) | 84.3 ± 11.5 | 81.8 ± 8.0 | .30 |
| High waist circumference b (n/%) | 14 (38%) | 12 (32%) | .46 |
| Diet (n/%) | 25 (68%) | 2 (5%) | <.001 |
| Gastrointestinal problems (n/%) | 28 (76%) | 5 (13.5%) | <.001 |
| Dysphagia (n/%) | 18 (49%) | 0 (0%) | <.001 |
P‐values ≤.02 (in bold) were considered significant.
BMI, body mass index; IQR, interquartile range; MD, mitochondrial disease.
a
Weight loss according to Global Leadership Initiative on Malnutrition (GLIM) criteria: >5% within past 6 months or >10% beyond 6 months. 29
b
High waist circumference >94 cm (women) and >80 cm (men) according to World Health Organization (WHO) 2008. 43