Table 1.
Demographics of eMERGE participants included in the CAAD GWAS, separated by CAAD case‐control status
| Case (N = 1793) | Control (N = 17,958) | Total (N = 19,751) | |
|---|---|---|---|
| Age (years) | |||
| Mean (SD) | 71.37 (9.70) | 63.45 (16.08) | 64.16 (15.77) |
| Range | 29.00–98.00 | 19.00–106.00 | 19.00–106.00 |
| Sex | |||
| Female | 667 (37.2%) | 10390 (57.9%) | 11057 (56.0%) |
| Male | 1126 (62.8%) | 7568 (42.1%) | 8694 (44.0%) |
| Racea | |||
| N‐Missb | 5 | 6 | 11 |
| African American | 61 (3.4%) | 4056 (22.6%) | 4117 (20.9%) |
| American Indian/Alaskan Native | 4 (0.2%) | 48 (0.3%) | 52 (0.3%) |
| Asian | 11 (0.6%) | 165 (0.9%) | 176 (0.9%) |
| Caucasian | 1664 (93.1%) | 12,214 (68.0%) | 13,878 (70.3%) |
| Native Hawaiian/Pacific Islander | 0 (0.0%) | 5 (0.0%) | 5 (0.0%) |
| Not reported | 4 (0.2%) | 83 (0.5%) | 87 (0.4%) |
| Unknown/Other | 44 (2.5%) | 1381 (7.7%) | 1425 (7.2%) |
| Ethnicitya | |||
| Hispanic/Latino | 35 (2.0%) | 1192 (6.6%) | 1227 (6.2%) |
| Non Hispanic/Latino | 1578 (88.0%) | 16,304 (90.8%) | 17,882 (90.5%) |
| Unknown | 180 (10.0%) | 462 (2.6%) | 642 (3.3%) |
| Ever smoker | |||
| N‐Miss | 350 | 7938 | 8288 |
| Ever | 1134 (78.6%) | 5024 (50.1%) | 6158 (53.7%) |
| Never | 309 (21.4%) | 4996 (49.9%) | 5305 (46.3%) |
| Median BMI (kg/m2) | |||
| N‐Miss | 279 | 6394 | 6673 |
| Mean (SD) | 28.59 (5.41) | 30.08 (7.47) | 29.90 (7.28) |
| Range | 17.86–56.98 | 14.10–80.86 | 14.10–80.86 |
| Coronary heart disease | |||
| N‐Miss | 138 | 3732 | 3870 |
| No | 631 (38.1%) | 11,051 (77.7%) | 11,682 (73.6%) |
| Yes | 1024 (61.9%) | 3175 (22.3%) | 4199 (26.4%) |
| Site | |||
| Geisinger | 591 (33.0%) | 1601 (8.9%) | 2192 (11.1%) |
| Harvard | 138 (7.7%) | 3732 (20.8%) | 3870 (19.6%) |
| Kaiser/University of Washington | 227 (12.7%) | 2260 (12.6%) | 2487 (12.6%) |
| Marshfield | 165 (9.2%) | 1920 (10.7%) | 2085 (10.6%) |
| Mayo | 407 (22.7%) | 235 (1.3%) | 642 (3.3%) |
| Mt. Sinai | 82 (4.6%) | 4279 (23.8%) | 4361 (22.1%) |
| Northwestern | 56 (3.1%) | 506 (2.8%) | 562 (2.8%) |
| Vanderbilt | 127 (7.1%) | 3425 (19.1%) | 3552 (18.0%) |
Abbreviations: BMI, body mass index; CAAD, Carotid artery atherosclerotic disease; eMERGE, electronic Medical Records and Genomics; GWAS, genome‐wide association studies.
a
Self‐reported race and ethnicity.
b
Number of missing values.