TABLE 2. Age-standardized mortality ratios (SMRs)* for persons with systemic lupus erythematosus (SLE),† overall and by sex, race,§ and Hispanic/Latino ethnicity¶—California Lupus Surveillance Project, 2007–2017.
Characteristic | No. of SLE patients | No. of observed deaths | No of expected deaths | SMR (95% CI) |
---|---|---|---|---|
Overall
|
812
|
135
|
45.7
|
3.0 (2.5–3.5)
|
Sex
| ||||
Female |
731 |
119 |
31.6 |
3.8 (3.1–4.5) |
Male |
81 |
16 |
5.6 |
2.9 (1.7–4.7) |
Race
| ||||
White |
312 |
45 |
20.0 |
2.3 (1.6–3.0) |
Black |
164 |
41 |
20.8 |
2.0 (1.4–2.7) |
Asian |
295 |
45 |
12.0 |
3.8 (2.7–5.0) |
Ethnicity (females and males)
| ||||
Hispanic/Latino |
123 |
19 |
4.9 |
3.9 (2.4–6.1) |
Race/Ethnicity (females)** | ||||
White |
283 |
40 |
13.8 |
2.9 (2.1–3.9) |
Black |
146 |
37 |
14.8 |
2.5 (1.8–3.4) |
Asian |
264 |
37 |
9.0 |
4.1 (2.9–5.7) |
Hispanic/Latina | 110 | 18 | 3.1 | 5.8 (3.5–9.2) |
Abbreviation: CI = confidence interval
* SMR is a ratio between the observed number of deaths in those with SLE and the number of deaths expected, based on age groups defined in CDC Wonder (https://wonder.cdc.gov). Sex, race and Hispanic/Latino ethnicity specific rates in San Francisco County were used, depending on the particular characteristic examined. CIs are calculated for each estimated SMR by assuming a Poisson distribution.
† Age in 2008 was used for adjustment.
§ Forty-one patients were excluded from race-specific analyses, including four who died: 22 had missing race information and 19 identified as a race other than White, Black or Asian, for which estimates are not available through CDC Wonder.
¶ Eighty-five patient records missing Hispanic/Latino ethnicity status, including four deaths, were excluded from ethnicity-specific estimates.
** For female-specific race and ethnicity analyses, crude rates for age group <15 years were not provided by CDC Wonder or were unreliable and therefore not included in calculations; there was insufficient sample size to generate specific race/ethnic estimates for men.