Fig 8. Heterologous expression of Tsu-ACR-16-like receptor in Caenohabditis elegans confer oxantel sensitivity to the recombinant worms Boxplot depicts number of thrashes/30 sec of worms in M9 media prior to incubation (0 h) and after 24 h incubation with (+) 500 μM oxantel.
The number of thrashes were significantly higher for wildtype C. elegans; N2 (red, n = 34) than each of the recombinant C. elegans N2;pmyo3::Tsu-acr-16-like lines: line 1 (yellow, P <0.0001, n = 28), line 2 (blue, P <0.0001, n = 30), line 3 (green, P <10−4, n = 34) when incubated in M9 media with 500 μM oxantel.