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. 2021 Feb 18;16(2):e0247132. doi: 10.1371/journal.pone.0247132

Fig 4. Effect of esc2-D430R on DNA damage sensitivity and the rate of accumulating dGCRs.

Fig 4

A) Spot assay to evaluate the growth of the esc2-D430R, mms21-CH and esc2-D430R mms21-CH mutants in response to hydroxyurea (HU) treatment. B) Spot assay to evaluate the growth of esc2 and mms21-CH mutants in response to methyl methanesulfonate (MMS) treatment. C) dGCR rates of esc2-D430R alone and together with siz1Δ siz2Δ and mms21-CH mutants. Error bars represent the upper and lower bounds of the 95% confidence interval with fold changes relative to WT shown above each respective analysis.