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. 2021 Feb 2;47(4):34. doi: 10.3892/ijmm.2021.4867

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Copyright: © Wu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Effects of GYY4137 on hypoxia-induced overproduction of reactive oxygen species in the mitochondria of CHs. Random micrographs of (A) DCFH-DA and (B) MitoSOX-derived fluorescence in CHs. Quantitative analysis of the mean fluorescence intensity was obtained in the indicated groups. Magnification, x200. (C and D) Effects of GYY4137 on superoxide dismutase and catalase activity in CHs. Data are presented as the means ± SEM (n=3). ^*P<0.05 vs. control; ^#P<0.05 vs. TBHP. CH, chondrocyte; DCFH-DA, 2′,7′-dichlorofluorescin diacetate; TBHP, tert-Butyl hydroperoxide.