Figure 2. West Nile virus (WNV) infection alters transcriptional regulation of the developmental and repair processes in the central nervous system (CNS).

(a–d) Enrichment of the developmental process and/or repair in WNV-infected cerebellum (a and b) and spinal cord (c and d) based on the ratios between GO term size (number of genes in term) and intersection size (number of differentially expressed genes annotated to term) at the advanced-symptomatic stage of WNV neurological disease (WNV-ND; 9 dpi). (e) Dissection of the molecular environment for axonal regeneration based on the differential transcriptional regulation of the molecules with established inhibitory or permissive roles in the regulation of axon growth.