Skip to main content
. 2021 Feb 18;10:e62273. doi: 10.7554/eLife.62273

Figure 5. Dissection of transcriptional regulation of cell death processes during advanced-symptomatic West Nile virus neurological disease (WNV-ND).

Figure 5.

(a) Comparative analysis of the number of upregulated genes annotated to significantly enriched (FDR < 0.05) terms associated with cell death processes (BP GO terms) and pathways (KEGG pathways; asterisks) in the cerebellum and spinal cord (numbers of upregulated genes annotated to each term and term sizes are indicated). (b) Venn diagram comparison of the upregulated genes annotated to the term ‘regulation of neuron death’ in the cerebellum and spinal cord with functional characterization of each indicated gene set (gene symbols and statistical details for enriched GO BP terms are provided for each component of Venn diagram; blank: not significant). (c) Percentages of genes in indicated cell-specific terms of interest that were upregulated in WNV-ND relative to the term size (calculated from data in a).