Figure 2.

Workflow for evaluation and refinement of familial hypercholesterolemia (FH) identification methods in Aim 1. Aim 1 will reconstruct family histories via automated methods and rigorously compare and evaluate 3 approaches for FH identification to refine these tools. EHR indicates electronic health record; PRIMUS, Pedigree and Identification of the Maximally Unrelated Set; RIFTEHR, The Relationship Inference from the Electronic Health Records; and SEARCH, Screening Employees and Residents in the Community for Hypercholesterolemia.