Table 1.
Nucleotide sequence similarity of the ACE-2 proteins of various animals to human ACE-2
| ACE-2 origin | Length of coding sequence (bp) | Similarity to human ACE-2 (%) | Position 31 | Position 353 | GenBank accession number |
|---|---|---|---|---|---|
| Homo sapiens (Human) | 2418 | 100 | K | K | AB046569.1 |
| Rhinolophus ferrumequinum (Greater horseshoe bat) | 2418 | 86.2 | D | K | AB297479.1 |
| Rhinolophus sinicus (Chinese horseshoe bat) | 2418 | 85.5 | E | K | GQ262791.1 |
| Macaca mulatta (Rhesus monkey)a | 2418 | 96.6 | K | K | NM_001135696.1 |
| Sus scrofa (Pig) | 2418 | 84.5 | K | K | NM_001123070.1 |
| Canis lupus familiaris (Dog) | 2415 | 87 | K | K | NM_001165260.1 |
| Capra hircus (Goat) | 2415 | 85.5 | K | K | KF921008.1 |
| Felis catus (Cat) | 2418 | 86.8 | K | K | AY957464.1 |
| Gallus gallus (Chicken) | 2427 | 68.1 | E | K | MK560199.1 |
| Manis javanica (Malayan pangolin) | 2418 | 86.5 | K | K | XM_017,650,257.1 |
| Notechis scutatus (Mainland tiger snake) | 2487 | 66.5 | Q | K | XM_026674969 |
| Mus musculus (Mouse) | 2418 | 85.2 | N | H | NM_001130513.1 |
a
NOTE: The sequence for Macaca mulatta (Rhesus monkey) provided here contains the natural mutation Y217N.