Fig. 1.

Pulmonary pathology of fatal COVID-19. a Incipient pulmonary damage in early-stage disease with intraalveolar edema, endothelial necrosis, microthrombosis, and endothelialitis. Insert with progressive inflammatory vascular injury with nuclear debris and granulocytes. (HE ×100) b Pneumocyte type 2 hyperplasia in exudative phase of DAD. (HE ×100) c Multiple intraalveolar giant cells in exudative phase DAD. (HE ×100) d Hyaline membranes and solid fibrin deposits in exudative phase DAD (HE ×100) e Thrombosis in small- to medium-sized vessels in early-stage lung disease (HE ×100) f Invasive aspergillosis as rare type of superinfection in late-stage DAD. (HE ×100) g Interstitial and intramural fibrosis and intraalveolar plugs of loose connective tissue in organizing phase of DAD. (HE ×100) h Massive bronchopulmonary squamous metaplasia in late stage organizing DAD. (HE ×100)