Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Dec 3;80(3):312–320. doi: 10.1136/annrheumdis-2020-218870

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

PMC Copyright notice

Proportion of patients achieving minimal disease activity (MDA) over 24 weeks. *p≤0.05; for upadacitinib 15 mg QD versus placebo; #p≤0.05; for upadacitinib 30 mg QD versus placebo; †significant in the multiplicity-controlled analysis. Results for MDA at week 24 are based on non-responder imputation with additional rescue handling, where MDA at week 24 for patients rescued at week 16 is imputed as non-responder. 95% CIs for response rate were calculated based on normal approximation to the binominal distribution. 95% CIs for response rate difference were calculated based on normal approximation. Nominal p value was constructed using Cochran-Mantel-Haenszel test adjusted for the main stratification factor of current disease-modifying antirheumatic drug use (yes/no). QD, once per day.