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. 2021 Feb 5;11:609592. doi: 10.3389/fphar.2020.609592

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Copyright © 2021 Xiong, Cao, Shen, Ma, Qiao, Shi, Ge, Ye, Zhang, Yuan, Zhang and Xia.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Evaluate the effect and cytotoxicity of the 44 compounds selected in the first round of screening. The 44 compounds and control (chloroquine diphosphate) were seriously diluted to analyze the cytotoxicity (A) and effect in inhibiting viral infection (B). Colorbar indicates cell viability (A) or inhibiton rate (B).