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. 2021 Feb 5;11:609592. doi: 10.3389/fphar.2020.609592

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Copyright © 2021 Xiong, Cao, Shen, Ma, Qiao, Shi, Ge, Ye, Zhang, Yuan, Zhang and Xia.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Analyze the inhibitory effect of 12 selected compounds in VSV-SARS-CoV-2-Sdel18 pseudovirus assay. The 12 compounds and control (chloroquine diphosphate) were seriously diluted to analyze the effect in inhibiting viral infection (A) and cytotoxicity (B). The IC50 and IC90 were calculated with non-linear regression.