TABLE 2.

Levodopa equivalent daily dose (LEDD) calculation. For drugs containing levodopa and other active components (e.g., carbidopa), we report the levodopa amount only.

Subject ID	Drug	Daily Dose (mg)	Conversion Factor	LED (mg)	Total, LEDD (mg)
1	Stalevo	375	1.33	499	699
	Rasagiline	1	100	100
	Amantadine	100	1	100
2	Rytary	170	0.6	102	602
	Pramipexole	3	100	300
	Amantadine	200	1	200
4	Stalevo	550	1.33	732	852
	Rotigotine	4	30	120
5	Stalevo	400	1.33	532	652
	Rotigotine	4	30	120
6	Sinemet	200	1	200	275
	Sinemet CR	100	0.75	75
7	Sinemet	300	1	300	300

We also show the conversion factors that lead to the LED calculation following Tomlinson et al. (2010) guidelines. Subject 3 is not reported since not currently treated with levodopa, dopamine agonists or other dopamine-interacting drugs.