Table 12.
The cytokines and secretomic genes shared between four tissue Treg (SP, LN, int, VAT) and four types of stem cells were summarized (hESCs_PMID: 22984290, hBMSCs_PMID: 22674502, hASCs_PMID: 20184379, and MSCs_PMID: 23685070).
| Tissue | Overlapped gene lists | Numbers of overlapped genes | Genes names |
|---|---|---|---|
| SP | [MSC] and [SP_Cytokines] and [hASCs] | 1 | LIF |
| LN | [LN_Secretome] and [hASCs] | 1 | PENK |
| [LN_Secretome] and [hBMSCs] | 1 | LAMC1 | |
| [LN_Secretome] and [hBMSCs] and [hASCs] | 2 | ECM1 | |
| CD44 | |||
| [LN_Cytokines] and [hASCs] | 1 | CRLF1 | |
| int | [int_Secretome] and [hASCs] | 1 | PENK |
| [int_Secretome] and [hBMSCs] and [hASCs]: | 1 | ECM1 | |
| [int_Secretome] and [hBMSCs]: | 2 | DKK3 | |
| LAMC1 | |||
| [int_Cytokines] and [int_Secretome]: | 2 | CSF1 | |
| IL6ST | |||
| VAT | [VAT_Secretome] and [hASCs] | 3 | PENK |
| CXCL2 | |||
| TFPI | |||
| [VAT_Secretome] and [hASCs] and [MSC] | 1 | LIF | |
| [VAT_Secretome] and [hBMSCs] and [hASCs] | 4 | IGFBP7 | |
| CST3 | |||
| LGALS1 | |||
| CD44 | |||
| [VAT_Secretome] and [hBMSCs]: | 4 | LAMC1 | |
| ANXA1 | |||
| LGALS3 | |||
| GRN | |||
| [VAT_Cytokines] and [hBMSCs] and [hASCs]: | 2 | MIF | |
| TIMP1 | |||
| [VAT_Cytokines] and [hASCs]: | 3 | CRLF1 | |
| CCL2 | |||
| CXCL6 | |||
| [VAT_Cytokines] and [VAT_Secretome]: | 2 | IL1R2 | |
| IL18 |
The Venn diagram figures were shown in Supplementary Figures 9A – 9D .