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. 2021 Feb 5;14:622257. doi: 10.3389/fnbeh.2020.622257

Figure 2.

Figure 2

Increased locomotor activity and anxiety-like behavior of Slit2-Tg mice observed in the open field test. (A,B) show the trajectories of mice in the open field test. (C) Total distance traveled. (D) The percentage of distance traveled in the middle. (E) Central travel durations: Slit2-Tg mice showed shorter central travel durations than wild-type (WT) mice. (F) Vertical activity. (G) Number of crossings. All data are expressed as means ± SEM. *p < 0.05, **p < 0.01, ****p < 0.0001 vs. WT mice. ##p < 0.01 (Slit2-Tg mice: 9 weeks, n = 30; 15 weeks, n = 20; 21 weeks, n = 10; WT mice: 9 weeks, n = 30; 15 weeks, n = 20; 21 weeks, n = 10).