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. 2021 Feb 5;14:622257. doi: 10.3389/fnbeh.2020.622257

Figure 3.

Figure 3

Slit2-Tg mice displayed increased anxiety-like behavior during the 5 min of the elevated plus maze test. (A,B) show the trajectories of mice in the elevated plus maze test. (C) Distance traveled. (D) Distance on the open arm (%). (E) Entry into open arms (%). (F) Time spent in the open arms (%). (G) Time spent in the closed arms (s). The elevated plus maze test showed decreased entry into the open arms in Slit2-Tg mice aged 21 weeks compared with wild-type (WT) mice of the same age. All data are expressed as means ± SEM, *p < 0.05, **p < 0.01, ****p < 0.0001 vs. WT mice. #p < 0.05, ##p < 0.01, ####p < 0.0001 (Slit2-Tg mice: 9 weeks, n = 30; 15 weeks, n = 20; 21 weeks, n = 10; WT mice: 9 weeks, n = 30; 15 weeks, n = 20; 21 weeks, n = 10).