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. 2020 Oct 16;394(3):533–543. doi: 10.1007/s00210-020-01998-9

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© The Author(s) 2020

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Fig. 5 — Mesalazine inhibits TGFβ-induced SMAD2/3 and ERK1/2 phosphorylation and reduces nuclear NFκB translocation. a Quantification and representative immunofluorescence images of NFκB (NFκB (p65) red; DAPI-stained nuclei blue) under control conditions, TGFβ and sequential TGFβ-mesalazine treatment (18 ≤ n ≤ 43 cells from each 4 independent coverslips). b Quantification of SMAD2/3 phosphorylation (pSMAD2/3) in HAF under control conditions, TGFβ and sequential TGFβ-mesalazine treatment (n = 4 per condition). c Quantification of ERK1/2 phosphorylation (p ERK1/2) in HAF fibroblasts under control conditions, TGFβ and sequential TGFβ-mesalazine treatment (n = 4 per condition). d Representative western blots for (b) and (c)