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. 2021 Feb 19;268(9):3116–3124. doi: 10.1007/s00415-021-10444-6

Table 1.

Total alpha-synuclein (αSyn) and enolase levels in serum and cerebrospinal fluid

COVID-19 with neurological symptoms COVID-19 without neurological symptoms Healthy controls p value
Age, years 65.0 (61.4–76.3)a 66.5 (65.9–68.4)a 66.5 (64–70.5)a
Sex, M/F 5/2 8/5 6/2
Serum αSyn, ng/ml 15.64 (13.3) (n = 7) 20.92 (18.1—26.9)a (n = 13) 26.82 (18.90) (n = 8) 0.27
CSF αSyn, pg/ml 324.2 (223.4) (n = 3) 256.5 (265.6) (n = 8) 0.71
Serum enolase, ng/ml 9.31 (4.7) (n = 7) 14.35 (8.9) (n = 13) 0.18

All data are displayed as Mean (SD), unless otherwise indicated

CSF cerebrospinal fluid, F: female, M male

aMedian (interquartile interval)