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. 2021 Feb 5;8:616489. doi: 10.3389/fmed.2021.616489

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Copyright © 2021 Li, Zhang, Sun, Liu, Manyande, Xu and Xiang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of fecal microbiota transplantation from DCP-CD or DCP-Non-CD mice on cognitive dysfunction in pseudo-germ-free mice. (A) Timeline of the establishment of pseud-germ-free mice and fecal transplantation. Antibiotics were dissolved in drinking water for 14 consecutive days. Fecal transplantation was performed for the other 14 consecutive days. ORT was performed on day 28. (B) ORT recognition index. N.S., not significant; ORT, Object recognition test.