Table 2.

Risk variant frequencies and results from Cox proportional hazards regression models with age at onset, sex, and genetic principal components as covariates.

Variant	Frequency	HR	95% CI for HR	p
APOE ε4	PDnD: 0.11	1.82	1.16–2.83	0.009*
	PDD: 0.14
MAPT H1/H1	PDnD: 0.68	1.71	1.06–2.78	0.03*
	PDD: 0.77

APOE, Apoliporotein E; HR, hazard ratio; CI, confidence interval; MAPT, microtubule-associated protein tau.

^*P value from the Wald test.