Table 1.

Cohort description.

	Inflamed dataset	Non-inflamed dataset	P values
Inflammation, no. (%)
Inflamed	112 [100]	0
Non-inflamed	0	168 [100]
Location, no. (%)
Colon	81 [72]	110 [65]	$P_{{\chi }^2}$ = 0.28
Ileum	31 [28]	58 [35]
Diagnosis, no. (%)
Crohn’s disease	63 [56]	110 [65]	$P_{{\chi }^2}$ = 0.29
IBD undefined	12 [11]	15 [9]
Ulcerative colitis	37 [33]	43 [26]
Sex, no. (%)
Female	68 [61]	103 [61]	$P_{{\chi }^2}$ = 1
Age at biopsy, mean ± SD	42.7 ± 15.1	42 ± 15.1	PWilcoxon = 0.61
Medication, yes (%)
Mesalazines	36 [32]	49 [29]	$P_{{\chi }^2}$ = 0.69
Steroids	26 [23]	31 [18]	$P_{{\chi }^2}$ = 0.38
Thiopurines	31 [28]	46 [27]	$P_{{\chi }^2}$ = 0.95
Methotrexate	1 [1]	4 [2]	NA
Anti-TNF	20 [18]	37 [22]	$P_{{\chi }^2}$ = 0.51
Montreal classification, no. (%)
Within CD
Montreal A
A1: <17 years	9 [14]	14 [13]	$P_{{\chi }^2}$ = 0.23
A2: 17–40 years	40 [63]	81 [74]
A3: >40 years	14 [22]	15 [14]
Montreal L
L1 (+L4)	9 (2) [14 (3)]	23 (3) [21 (3)]	$P_{{\chi }^2}$ = 0.23
L2 (+L4)	14 (2) [22 (3)]	17 (2) [15 (2)]
L3 (+L4)	29 (7) [46 (11)]	55 (10) [50 (9)]
Montreal B	[1 missing]	[1 missing]
B1 (p)	17 (11) [27 (17)]	37 (17) [34 (16)]	$P_{{\chi }^2}$ = 0.49
B2 (P)	16 (9) [25 (14)]	23 (16) [21 (15)]
B3 (P)	6 (3) [10 (5)]	7 (9) [6 (8)]
Within UC + IBDU
Montreal E	[5 missing]	[4 missing]
E1	2 [5]	2 [4]	$P_{{\chi }^2}$ = 0.93
E2	15 [34]	17 [31]
E3	27 [61]	35 [65]
Montreal S	[11 missing]	[15 missing]	$P_{{\chi }^2}$  = 0.93
S1	0	1 [2]
S2	6 [16]	7 [16]
S3	20 [53]	23 [53]
S4	12 [32]	12 [28]

P values of comparing categorical variables between groups are from two-sided χ² test; P values of comparing continuous variable between two groups are from two-sided Wilcoxon’s test.