Figure 3.

Three-dimensional (3D) bioengineering platforms used to study partial EMT phenotype

(A) 96-well low attachment plate.

(B) Hanging drop spheroid culture method, adapted with permission Kuo et al. (2017).

(C) Soft-agar-coated spheroid model, adapted with permission from Chaicharoenaudomrung et al. (2019).

(D) Collagen matrix for studying microenvironment interactions with tumor cells, adapted with permission from Kasai et al., (2017).

(E) Microfluidic platform, reproduced from Kuo et al. (2014) with permission from The Royal Society of Chemistry.

(F) Breast tumor cells-adipocytes co-culture model, adapted with permission from cross-reference to Debnath et al. (2003).