Table 2.
Changes of clinical variables after levodopa intake.
| Variable | OFF | ON | Mean change after levodopa intake (95% CI) | p-Value |
|---|---|---|---|---|
| Total n = 50 | Total n = 50 | |||
| Mean (±SD) | Mean (±SD) | |||
| UPDRS part II | 21.59 (±7.43) | 8.63 (±4.96) | 12.95 (11.04–14.87) |
<0.001 |
| UPDRS part III | 40.00 (±13.50) | 15.78 (±7.57) | 24.22 (21.27–27.16) |
<0.001 |
| UPDRS III item 18 (speech item) | 1.68 (±0.68) | 0.94 (±0.71) | 0.74 (0.58–0.90) |
<0.001 |
| PIGD subscore | 9.48 (±4.14) | 3.78 (±2.89) | 5.70 (4.72–6.67) |
<0.001 |
| Speech subscore | 3.32 (±1.31) | 1.72 (±1.32) | 1.60 (1.24–1.95) |
<0.001 |
UPDRS, Unified Parkinson's Disease Rating Scale; PIGD, Postural Instability Gait Disorders.