Table 1.
Study participants' baseline characteristics in the discovery and replication datasets.
| Study | Ethnicity1 | N | Age (years) | BMI (kg/m2) | Systolic BP (mmHg) | Diastolic BP (mmHg) | Medication (%) | Hypertension (%)2 |
|---|---|---|---|---|---|---|---|---|
| Discovery data | ||||||||
| ARIC | AA | 2764 | 53.49 (5.81) | 29.72 (5.99) | 128.56 (20.90) | 79.91 (12.10) | 1236 (45%) | 1633 (60%) |
| EA | 9170 | 54.36 (5.68) | 27.00 (4.80) | 118.48 (16.86) | 71.64 (9.95) | 2333 (25%) | 2951 (32%) | |
| Bambui | Brazilians | 1439 | 69.09 (7.19) | 25.14(4.97) | 137.34 (22.54) | 83.41 (12.72) | 735 (51%) | 1109 (77%) |
| HABC | AA | 1115 | 73.43 (2.89) | 28.54 (5.35) | 138.82 (22.44) | 73.42 (12.70) | 699 (63%) | 860 (77%) |
| EA | 1641 | 73.77 (2.84) | 26.63 (4.13) | 133.55 (20.11) | 69.86 (11.13) | 816 (50%) | 1067 (65%) | |
| MESA | AA | 1425 | 62.00 (10.07) | 30.23 (5.90) | 131.50 (21.42) | 74.48 (10.15) | 684 (48%) | 849 (60%) |
| EA | 2326 | 62.66 (10.27) | 27.83 (5.05) | 123.67 (20.46) | 70.20 (9.92) | 626 (27%) | 895 (38%) | |
| Chinese | 703 | 62.61 (10.42) | 23.96 (3.33) | 124.01 (21.43) | 71.82 (10.36) | 195 (28%) | 268 (38%) | |
| Hispanics | 1317 | 61.48 (10.38) | 29.45 (5.16) | 126.83 (22.12) | 71.49 (10.08) | 389 (30%) | 548 (42%) | |
| Total | 21,900 | |||||||
| Replication data | ||||||||
| WHI | AA | 6500 | 61.14(6.86) | 31.04(6.29) | 131.40(17.84) | 78.02(9.48) | 2982(46%) | 3954 (61%) |
| Hispanics | 2869 | 60.55(6.55) | 28.81(5.42) | 125.08(16.94) | 74.83(9.48) | 601(21%) | 995 (35%) | |
| Framingham | EA | 2451 | 55.39(9.39) | 27.43(4.16) | 126.10(18.65) | 74.57(9.84) | 396(16%) | 763(31%) |
| Total | 11,820 | |||||||
| Total | 33,720 | |||||||
1AA = African Americans and EA = European Americans.
2Hypertension was defined as SBP at least 140 mmHg, DBP at least 90 mmHg, or being on antihypertensive medication.
Mean (SD) reported, except where indicated.