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. 2021 Feb 18;11:4184. doi: 10.1038/s41598-021-83669-0

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Receptive field size was not altered in any RGC type following acute IOP elevation. (A, B) The receptive field (RF) size calculated from the spike-triggered average of an ON (A) and OFF (B) RGC. Some cells that did not respond to the full field stimuli (NFFR cells) showed an STA response while others that were full field responsive had no STA, thus cells were still classified on their full field response and those with STAs compared. None of the RGC subtypes showed a change in receptive field size in sham (white bars) relative to IOP elevated (red bars) eyes (C). Numbers in histograms indicate number of cells recorded from n = 6–10 animals.