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. 2020 Nov 4;3(2):182–194. doi: 10.1016/j.cjco.2020.10.015

Figure 4.

Figure 4

Intracellular colocalization of ghrelin and natriuretic peptide type-B (BNP) in (A) control left ventricle (LV), (B) diseased LV tissue, and (C) left atrium (LA). (A-C) Representative confocal fluorescent images of ghrelin (green) and BNP (red) in healthy and diseased tissue shows correlation of ghrelin and BNP in the merged images. DAPI (blue) indicates nuclear staining. White arrows indicate areas of punctate staining and colocalization in the merged images. (D) Pearson coefficient correlation (PCC) values indicate a stronger correlation in the healthy tissue (n = 10) compared with the diseased tissue in the LA (P = 0.0040; n = 29) but not the LV (P = not significant; n = 29). Values are mean ± SD.