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. 2020 Nov 4;3(2):182–194. doi: 10.1016/j.cjco.2020.10.015

Figure 5.

Figure 5

(A) Representative fluorescent confocal images of [Dpr3(n-octanoyl),Lys19(sulfo-Cy5)]ghrelin(1-19) (Cy5-ghrelin(1-19; red), ghrelin (green), natriuretic peptide type-B (BNP) (magenta), and sarcoplasmic reticulum ATPase pump (SERCA2a; green) in cardiac tissue of the left atrium (LA; A in top panels) and the left ventricle (LV; B middle panels). DAPI (blue) nuclear stain in all images. Graphs indicate fluorescence intensities represented by integrated densities where each dot represents 1 patient sample. A significant linear regression is present in only the LV between SERCA2a and (C) Cy5-ghrelin(1-19; r = 0.7893; P = 0.0348; LA n = 15, LV n = 8), (D) ghrelin (r = 0.7315; P = 0.0392; LA n = 15, LV n = 8), and (E) natriuretic peptide type-B (BNP; r = 0.8401; P = 0.0180; LA n = 14, LV n = 7).