Fig. 1.

Structure of the trimeric S-protein of SARS-CoV-2 in the prefusion conformation. Chain A is shown in ribbon representation with their seven structural domains colored by blue for NTD, red for SD1, green for RBD, tan for SD2, cyan for FP, yellow for HR1-CH and violet for CD. The RBD of Chain A is in the up conformation whereas Chain B and C are in down conformation. Chain B and C are shown in surface representations with powder-blue and light-yellow colors respectively. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)