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. 2021 Feb 19;25:101044. doi: 10.1016/j.genrep.2021.101044

Table 4.

Percentage of synonymous (syn) and non-synonymous (non-syn) mutation in three different codon positions (CP)-1st/2nd/3rd in each of the SARS-CoV-2 protein.

Protein CP Type Percentage
E 1st Non-syn 100.00
M 1st Non-syn 26.67
M 1st Syn 6.67
N 1st Non-syn 33.96
N 1st Syn 1.89
ORF10 1st Non-syn 50.00
ORF1ab 1st Non-syn 22.80
ORF1ab 1st Syn 2.74
ORF3a 1st Non-syn 33.33
ORF7a 1st Non-syn 40.00
ORF7b 1st Non-syn 50.00
ORF8 1st Non-syn 30.00
S 1st Non-syn 20.48
S 1st Syn 1.20
M 2nd Non-syn 20.00
N 2nd Non-syn 26.42
ORF1ab 2nd Non-syn 26.44
ORF3a 2nd Non-syn 30.30
ORF7a 2nd Non-syn 20.00
ORF7b 2nd Non-syn 50.00
ORF8 2nd Non-syn 60.00
S 2nd Non-syn 28.92
M 3rd Syn 46.67
N 3rd Non-syn 9.43
N 3rd Syn 28.30
ORF10 3rd Syn 50.00
ORF1ab 3rd Non-syn 8.51
ORF1ab 3rd Syn 39.51
ORF3a 3rd Non-syn 9.09
ORF3a 3rd Syn 27.27
ORF6 3rd Non-syn 50.00
ORF6 3rd Syn 50.00
ORF7a 3rd Syn 40.00
ORF8 3rd Syn 10.00
S 3rd Non-syn 15.66
S 3rd Syn 33.73