Table 2.
Significantly differentially expressed genes with immunological relevance: relative gene overexpression in patients with phlegmonous appendicitis
| Gene | Mean signal PA | Mean signal GA | P † |
|---|---|---|---|
| MHC class II | 142 | 65 | 0·043 |
| HLA-F | 2395 | 1585 | 0·024 |
| HLA-DOB | 185 | 119 | 0·017 |
| CD40L * | 444 | 250 | 0·003 |
| CD2 | 715 | 304 | 0·027 |
| CD3 | 224 | 121 | 0·021 |
| CD24 | 144 | 87 | 0·021 |
| CD23 | 582 | 276 | 0·010 |
| CD72 | 47 | 27 | 0·023 |
| NIK | 150 | 83 | 0·029 |
| TRAF1 | 147 | 93 | 0·042 |
| CD79 * | 4384 | 3148 | 0·004 |
| Pol-III | 66 | 42 | 0·037 |
| Interleukin 23 | 74 | 30 | 0·027 |
| TCR β variable 2 | 19 | 7 | 0·012 |
| TCR β variable 3-1 | 7 | 3 | 0·019 |
| TCR β variable 4-2 | 45 | 29 | 0·013 |
| TCR β variable 5-5 * | 7 | 4 | 0·002 |
| TCR β variable 5-6 * | 11 | 5 | < 0·001 |
| TCR β variable 6 | 55 | 27 | 0·013 |
| TCR β variable 6-5 | 31 | 11 | 0·024 |
| TCR β variable 6-6 | 23 | 9 | 0·015 |
| TCR β variable 6-8 * | 35 | 13 | 0·003 |
| TCR β variable 7-4 * | 17 | 7 | 0·008 |
| TCR β variable 7-7 * | 7 | 2 | < 0·001 |
| TCR β variable 11-1 * | 13 | 6 | 0·002 |
| TCR β variable 11-3 * | 6 | 2 | 0·003 |
| TCR β variable 14 | 23 | 9 | 0·045 |
| TCR β variable 15 | 6 | 2 | 0·019 |
| TCR β variable 18 | 17 | 8 | 0·022 |
| TCR β variable 29-1 | 51 | 23 | 0·036 |
| TCR a variable 1-2 | 19 | 10 | 0·016 |
| TCR α variable 2 | 10 | 5 | 0·021 |
| TCR α variable 8-6 | 15 | 8 | 0·042 |
| TCR α variable 10 | 6 | 4 | 0·026 |
| TCR α variable 12-1 * | 7 | 3 | 0·007 |
| TCR α variable 12-2 | 19 | 11 | 0·032 |
| TCR α variable 16 | 8 | 3 | 0·018 |
| TCR α variable 17 | 17 | 10 | 0·044 |
| TCR α variable 19 * | 23 | 10 | 0·004 |
| TCR α variable 22 | 19 | 10 | 0·042 |
| TCR α variable 23 | 17 | 8 | 0·021 |
| TCR α variable 24 | 9 | 5 | 0·019 |
| TCR α variable 26-1 | 8 | 6 | 0·048 |
| TCR α variable 35 * | 7 | 3 | 0·006 |
| TCR α variable 38-2 | 25 | 15 | 0·028 |
| TCR α variable 41 * | 18 | 11 | 0·003 |
*Gene expression within the top 100 differentially expressed genes (based on P values). PA, phlegmonous appendicitis; GA, gangrenous appendicitis.
†Welch’s test.