Fig. 6.

Subgroup model generation for individualized prediction of postoperative 30-day mortality

Generalized additive models with smoothing splines were used, as illustrated for postoperative 30-day mortality in patient subgroups: a major resection, b minor resection, c perihilar cholangiocarcinoma (CCA), d metastatic disease to the liver, e hepatocellular carcinoma (HCC), and f CCA. Shaded areas represent 95 per cent confidence intervals. Based on the respective model, the combined aspartate aminotransferase/platelet ratio index/albumin–bilirubin grade (APRI/ALBI) score was grouped into deciles and individual risk for each subgroup is shown in the lower panel. Number of patients in each decile is also shown.