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. 2021 Jan 22;5(1):zraa034. doi: 10.1093/bjsopen/zraa034

Table 4.

Cox regression analysis of risk factors for complicated appendicitis

Hazard ratio P
Age (years)
 <45 1.00 (reference) 0.004
 45–60 1.45
(0.99, 2.12)
0.055
 >60 1.85
(1.28, 2.66)
0.001
Pre-CT delay (h)*
 <24 1.00 (reference) < 0.001
 24–48 0.97
(0.63, 1.48)
0.877
 >48 2.05
(1.32, 3.20)
0.001
Body temperature (°C)
 ≤37.0 1.00 (reference) < 0.001
 37.1–37.9 1.51
(1.04, 2.20)
0.029
 ≥38.0 2.38
(1.56, 3.65)
< 0.001
WBC count > 13×109/l 1.40
(1.03, 1.88)
0.030
C-reactive protein (mg/l)
 ≤50 1.00 (reference) 0.021
 51–100 1.15
(0.75, 1.75)
0.526
 >100 1.75
(1.14, 2.67)
0.009
Extraluminal free air on CT 1.47
(0.60, 3.56)
0.398
Periappendiceal fluid on CT 2.11
(1.39, 3.19)
< 0.001
Appendicolith on CT 2.71
(2.01, 3.64)
< 0.001
Time from CT to antibiotics started (h) 0.94
(0.90, 0.97)
< 0.001

Values in parentheses are 95 per cent confidence intervals.

*Pre-CT delay is time from CT to start of operation; time to event is time from CT to surgery. WBC, white blood cell.