Table 1.
No. (%) | ||||
---|---|---|---|---|
Moderate (n=10) | Severe (n=10) | Critically ill (n=10) | P-value | |
Age | 63±14 | 63±25 | 67±10 | 0.87 |
Sex | ||||
Female | 2(20) | 4(40) | 6(60) | 0.19 |
Male | 8(80) | 6(60) | 4(40) | |
Comorbidities | ||||
Hypertension | 6(60) | 6(60) | 4(40) | 0.59 |
Diabetes | 5(50) | 4(40) | 6(60) | 0.67 |
Cardiovascular disease | 3(30) | 3(30) | 2(20) | 0.84 |
Cerebrovascular disease | 2(20) | 3(30) | 2(20) | 0.83 |
Malignancy | 0 | 1(10) | 2(20) | 0.33 |
Signs and symptoms | ||||
Fever | 9(90) | 10(100) | 10(100) | >0.99 |
Highest temperature, °C | ||||
<37.3 | 2(20) | 2(20) | 0 | 0.32 |
37.3-38.0 | 5(50) | 0 | 4(40) | 0.04 |
38.1-39.0 | 3(30) | 0 | 0 | 0.04 |
>39.0 | 0 | 8(80) | 6(60) | <0.01 |
Fatigue | 5(50) | 2(20) | 7(70) | 0.08 |
Cough | 5(50) | 3(30) | 7(70) | 0.20 |
Dyspnea | 3(30) | 3(30) | 7(70) | 0.11 |
Expectoration | 1(10) | 0 | 0 | 0.36 |
Pharyngalgia | 1(10) | 0 | 0 | 0.36 |
Systolic pressure, mm Hg | 139±19 | 138±31 | 132±20 | 0.79 |
Diastolic pressure, mm Hg | 82±15 | 82±7 | 83±7 | 0.96 |
Heart rate, | 88±16 | 104±9 | 111±21 | 0.04 |
Respiratory rate | 21±4 | 21±5 | 21±6 | 0.06 |
Oxygen saturation | 97±2 | 74±14 | 55±16 | <0.01 |
Main treatment | ||||
Arbidol | 6(60) | 10(100) | 4(40) | 0.02 |
Resochin | 1(10) | 2(20) | 0 | 0.33 |
Ribavirin | 1(10) | 7(70) | 6(60) | 0.02 |
Glucocorticoid therapy | 0 | 8(80) | 6(60) | <0.01 |
Antibiotic therapy | 9(90) | 10(100) | 10(100) | >0.99 |
Chinese traditional medicine | 9(90) | 8(80) | 6(60) | 0.27 |
Oxygen inhalation | 7(70) | 10(100) | 10(100) | 0.04 |
NIV | 7(70) | 3(30) | 1(10) | 0.02 |
IMV | 0 | 7(70) | 9(90) | <0.01 |
CT image | ||||
Bilateral distribution of patchy shadows or ground-glass opacity, No. (%) | 10(100) | 10(100) | 10(100) | |
Survive % | 100% | 80% | 10% | <0.01 |
Data are Means ± SDs, where N is the total number of patients with available data. P-values comparing the three groups are from chi-square, Fisher's exact test, and ANOVA. NIV = non-invasive ventilation. IMV = invasive mechanical ventilation. P < .05 was considered statistically significant.