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. 2021 Jan 14;17(2):574–588. doi: 10.7150/ijbs.52097

Figure 3.

Figure 3

CA125 induced ovarian cancer cell migration by attenuating DKK1 expression. OVCAR3 cells (A) transfected with pEGFP-N1 vector and pEGFP-N1-DKK1 and A2780 (B) transfected with negative control (NC) and siDKK1 were subjected to Transwell migration assays and treated for 48 h with CA125 (scale bars=100 µm). (C) (D) Cell counts across the Transwell membrane. The statistical analyses were conducted with the number of invaded cells (indicated by red arrows). The results represent the mean ± SD. *p<0.05, **p<0.01, *** p<0.001.