Figure 7.

CA125 facilitates ovarian cancer metastasis in vivo. (A) The effect of CA125 on tumor growth was monitored by measuring tumor volume consecutively. Individual tumor images (B) and lymphatic tissue images (C) were taken after the mice were sacrificed. (D) Representative micrographs of hematoxylin and eosin (H&E) staining (scale bars=100 µm). Red arrows indicate metastases. Green arrows indicate normal lymphatic vessels. (E) The percentages of positive lymphatic vessels in the inguinal and axillary lymphatic tissues. The results represent the mean ± SD. (F) LYVE-1 histochemical staining of inguinal and axillary lymphatic tissues. The red arrow shows the tumor cells in the lymphatic vessel (scale bars=100 µm).