Figure 4.

The expectation of circRNAs in prostate cancer. Firstly, abundant and adequate quantities of circRNAs are measured in prostate cancer (PC) from fluid and tissues biopsies with noticeable stability and specificity, which can be conferred the capacities of prognosis and diagnosis. In addition, accumulating researches proved that circRNAs in exosomes exhibit indispensable properties in cancer progression via the function of concentration and targeting. So detecting the level of distinct circRNA in exosomes creates and extends the region of cancer screening and diagnosis in PC. Moreover, it is of importance and well established that CRISPR/Cas9 system directly modify the mutations and mistakes leading to cancer. This novel and practical technology may become a promising candidate with clinical potential in addressing therapeutic issues in PC by suppressing and activating specific molecules.