Table 2. Model Fits for Four Different Bayesian Linear Mixed-Effects Models Examining the Difference in TSPO Binding (Estimated Using VT) Between Patients With Psychosis and Healthy Control Subjects.
Region | Model | dLOOC | dWAIC | Akaike Weighta (%) |
---|---|---|---|---|
Frontal Cortex | 0 | 7.6 | 7.6 | 1 |
1 | 0 | 0 | 38 | |
2 | 0.8 | 0.8 | 26 | |
3 | 1.1 | 1.1 | 22 | |
4 | 1.9 | 1.9 | 14 | |
Temporal Cortex | 0 | 7.1 | 7.1 | 1 |
1 | 0 | 0 | 35 | |
2 | 0.6 | 0.6 | 26 | |
3 | 0.9 | 0.9 | 22 | |
4 | 1.6 | 1.6 | 16 | |
Hippocampus | 0 | 15.3 | 15.4 | < 1 |
1 | 0 | 0 | 36 | |
2 | 0.4 | 0.4 | 29 | |
3 | 1.3 | 1.2 | 19 | |
4 | 1.7 | 1.6 | 16 |
A null model (0) without patient–control status as predictor is included as a baseline comparison. Lower dLOOC and dWAIC values indicate better model fit.
dLOOC, distance to best-fitting model calculated using leave-one-out cross-validation; dWAIC, distance to best-fitting model calculated using widely applicable information criteria; TSPO, translocator protein; VT, total distribution volume.
Weights calculated using LOOC scores.