Table 3. Summary of Kinetic Reaction Profiles Derived from Solvent Screening Studies^a.

entry	solvent	t (h)b	4b yield (%)	dehydration: 4c + 4d + 4e yield (%)	carbon mass balance (%)	cis–trans ratio 4b
1	water	0.5	49	40	89	64:36
2	MeOH	0.75	46	34	80	65:35
3	EtOH	0.75	56	36	92	67:33
4	n-PrOH	1.5	61	28	89	67:33
5	i-PrOH	2	69	27	96	71:29
6	n-BuOH	1	36	53	89	69:33
7	i-BuOH	3	61	25	86	68:32
8	s-BuOH	3	72	22	94	67:33
9	t-BuOH	3	74	21	95	67:33
10	EtOAc	4	62	37	99	69:31
11	CPME	2	62	36	98	69:31
12	THF	7	65	31	96	71:29
13	dioxane	2	69	29	98	68:32
14c	toluene	7	26	73	99	71:29
15c	heptane	7	29	69	98	52:48

^aReaction conditions: 50 mmol of 4 and 5.1 wt % Ru/C, 100 °C, 50 bar H_2.

^bSpecific reaction time upon which complete conversion was observed via GC-FID.

^cThe reaction was run for 7 h without collection of kinetic samples. Since the diol products emulsified out of the solvent, the entire reaction mixture was dissolved in acetonitrile for GC analysis.