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. Author manuscript; available in PMC: 2021 Feb 19.
Published in final edited form as: Hepatology. 2019 Apr 25;70(1):389–402. doi: 10.1002/hep.30612

Fig. 6. Relative mRNA levels of BA related genes for male WT, Cyp7a1−/−, Cyp27a1−/−, and DKO mice.

Fig. 6.

Genes were measured using RT q-PCR, normalized to β-actin mRNA levels, and graphed as relative mRNA ± 1 SD. An asterisk denotes a significant difference from WT (P < 0.05). (A) Relative mRNA of hepatic genes involved in classic, alternative, and minor BA synthetic pathways. (B) Relative mRNA of hepatic genes for BA conjugation. (C) Relative mRNA of hepatic FXR, Shp, Fgfr4, Ntcp, and Bsep. (D) Relative mRNA of ileal genes involved in BA regulation and transport.