Table 3.
Spearman correlation coefficients and quantile regression models of the degree of spousal concordance in pathophysiological markers and type 2 diabetes risk factors
| n | rs (95% CI) | Men | Women | |||||
| n | Age-adjusted | Multivariable-adjusted | n | Age-adjusted | Multivariable-adjusted | |||
| Beta coefficient (95% CI) | Beta coefficient (95% CI) | |||||||
| Risk factors | ||||||||
| Physical activity dimensions | ||||||||
| Time in LPA | 248 | 0.27 (0.14 to 0.38) | 246 | 0.28 (0.13 to 0.58) | 0.33 (0.12 to 0.59) | 241 | 0.22 (0.11 to 0.34) | 0.18 (0.16 to 0.33) |
| Time in HPA | 248 | 0.36 (0.24 to 0.47) | 246 | 0.34 (0.20 to 0.48) | 0.35 (0.23 to 0.43) | 241 | 0.30 (0.14 to 0.59) | 0.28 (0.09 to 0.53) |
| Sedentary time | 248 | 0.17 (0.03 to 0.29) | 246 | 0.21 (−0.01 to 0.39) | 0.22 (0.01 to 0.37) | 241 | 0.16 (−0.02 to 0.31) | 0.11 (−0.02 to 0.34) |
| Diet indicators | ||||||||
| Dutch Healthy Diet Index | 307 | 0.42 (0.33 to 0.52) | 263 | 0.45 (0.28 to 0.61) | 0.42 (0.31 to 0.54) | 248 | 0.35 (0.21 to 0.51) | 0.29 (0.19 to 0.45) |
| Total energy intake | 307 | 0.26 (0.15 to0.36) | 263 | 0.25 (0.12 to 0.50) | 0.28 (0.12 to 0.47) | 248 | 0.32 (0.21 to 0.43) | 0.30 (0.18 to 0.41) |
| Adiposity measures | ||||||||
| BMI | 326 | 0.33 (0.24 to 0.42) | 272 | 0.31 (0.16 to 0.35) | 0.26 (0.20 to 0.35) | 254 | 0.21 (0.15 to 0.45) | 0.21 (0.05 to 0.35) |
| Percentage of body fat | 325 | 0.24 (0.14 to 0.34) | 271 | 0.33 (0.10 to 0.48) | 0.28 (0.06 to 0.49) | 253 | 0.20 (0.04 to 0.33) | 0.18 (0.01 to 0.28) |
| Waist circumference | 326 | 0.32 (0.22 to 0.43) | 272 | 0.36 (0.24 to 0.48) | 0.19 (0.07 to 0.32) | 254 | 0.20 (0.13 to 0.41) | 0.19 (0.10 to 0.35) |
| Waist to hip ratio | 326 | 0.21 (0.09 to 0.32) | 272 | 0.24 (0.03 to 0.39) | 0.09 (−0.06 to 0.31) | 254 | 0.18 (0.07 to 0.34) | 0.19 (0.00 to 0.30) |
| Pathophysiological markers | ||||||||
| Matsuda Index | 269 | 0.16 (0.03 to 0.28) | 233 | 0.06 (−0.05 to 0.13) | −0.00 (−0.08 to 0.11) | 225 | 0.19 (0.05 to 0.41) | 0.11 (−0.03 to 0.27) |
| HOMA2-IR | 302 | 0.19 (0.07 to 0.30) | 263 | 0.21 (0.03 to 0.49) | 0.07 (−0.01 to 0.30) | 253 | 0.13 (0.02 to 0.34) | 0.09 (0.03 to 0.19) |
| C-peptidogenic indext30 | 270 | 0.10 (−0.01 to 0.22) | 234 | 0.03 (−0.02 to 0.13) | 0.03 (−0.03 to 0.12) | 226 | 0.16 (0.05 to 0.43) | 0.15 (0.03 to 0.42) |
| Rate sensitivity | 233 | 0.11 (−0.01 to 0.24) | 202 | 0.18 (−0.10 to 0.32) | 0.17 (−0.09 to 0.28) | 197 | 0.11 (−0.06 to 0.22) | 0.13 (−0.07 to 0.20) |
| C peptide AUC | 269 | 0.07 (−0.05 to 0.19) | 233 | 0.13 (−0.09 to 0.24) | 0.07 (−0.04 to 0.20) | 225 | 0.05 (−0.05 to 0.32) | 0.05 (−0.07 to 0.31) |
| Glucose sensitivity | 273 | 0.09 (−0.02 to 0.21) | 239 | 0.04 (−0.09 to 0.33) | 0.07 (0.01 to 0.18) | 231 | 0.04 (−0.09 to 0.26) | 0.03 (−0.12 to 0.22) |
| Potentiation factor | 284 | −0.00 (−0.11 to 0.11) | 246 | 0.01 (−0.11 to 0.07) | 0.00 (−0.14 to 0.07) | 237 | 0.03 (−0.14 to 0.17) | 0.09 (−0.10 to 0.19) |
| Disposition index | 268 | 0.23 (0.10 to 0.35) | 232 | 0.12 (0.04 to 0.24) | 0.09 (−0.01 to 0.16) | 224 | 0.26 (0.20 to 0.52) | 0.15 (0.01 to 0.48) |
| Glucose metabolism indicators | ||||||||
| Fasting glucose | 326 | 0.25 (0.14 to 0.34) | 280 | 0.37 (0.07 to 0.56) | 0.30 (0.05 to 0.51) | 269 | 0.17 (0.06 to 0.30) | 0.12 (0.05 to 0.22) |
| 2-hour plasma glucose | 308 | 0.15 (0.03 to 0.27) | 276 | 0.15 (−0.00 to 0.31) | 0.07 (−0.02 to 0.16) | 262 | 0.06 (0.01 to 0.18) | 0.10 (−0.05 to 0.16) |
| Hemoglobin A1c | 324 | 0.20 (0.09 to 0.30) | 282 | 0.23 (0.01 to 0.36) | 0.15 (−0.05 to 0.30) | 267 | 0.10 (−0.04 to 0.22) | 0.08 (−0.00 to 0.19) |
rs is Spearman correlation coefficient.
Physical activity dimensions were adjusted for age, educational level, alcohol use and smoking status. The Dutch Healthy Diet Index was adjusted for age, educational level, waist circumference, smoking status and total energy intake. Adiposity measures were adjusted for age, time in HPA, smoking status, Dutch Healthy Diet Index and educational level. Pathophysiological markers were adjusted for age, waist circumference, time in HPA and family history of diabetes.
AUC, area under the curve; BMI, body mass index; HOMA2-IR, Homeostatic Model Assessment of Insulin Resistance; HPA, high-intensity physical activity; LPA, low-intensity physical activity.