Figure 2.

miR-429 mimic elevates the inhibition rate of resistant colorectal cancer cells treated with nintedanib. (A) Transfection efficiency of the miR-429 mimic was detected by reverse transcription-quantitative PCR. Control group consisted of untransfected cells. ***P<0.001 vs. control; ^###P<0.001 vs. mimic NC. (B) IC₅₀ value and inhibition rate of cells treated with different concentrations of nintedanib post-transfection, as determined by Cell Counting Kit-8 assay. miR-429, microRNA-429; NC, negative control; -R, resistant to nintedanib.