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. 2021 Jan 28;23(4):239. doi: 10.3892/mmr.2021.11878

Table I.

HIF-1α is involved in the regulatory network of non-coding RNAs.

Author, year RNA type Tissues/cells Signal pathways Investigated processes (Refs.)
Liu et al, 2015 miRNAs Rat brain miR-335/HIF-1α Death (35)
Serocki et al, 2018 Various endothelial cells miR-155 and miR-18a/HIF-1α Angiogenesis and hypoxia; proliferation and migration (188)
Wang et al, 2015 lncRNAs Human nucleus pulposus cells RP11-296A18.3/miR-138/HIF-1α Proliferation and ECM synthesis (53)
Bao et al, 2018 Human vascular endothelial cells LINC00657/miR-590-3p/HIF-1α/VEGF/MMP2 Angiogenesis (189)
Liang et al, 2017 circRNAs Human breast cancer circDENND4C/HIF-1α Proliferation (186)
Du et al, 2017 Human and mice hearts circ-Foxo3/HIF-1α Senescence (187)
Dang et al, 2017 Human vascular endothelial cells circ_0010729/miR-186/HIF-1α Proliferation and apoptosis (190)
Liu et al, 2017 Human osteosarcoma endothelial cells circRNA_103801/HIF-1α/VEGF Cancer pathway (191)

HIF-1α, hypoxia-inducible factor-1α; ECM, extracellular matrix; VEGF, vascular endothelial growth factor; MMP2, matrix metalloproteinase 2; miR, microRNA; lncRNA, long non coding RNA; circRNA, circular RNA.