Figure 1.

miR-199a expression is downregulated in OC tissues, peripheral blood and cell lines. (A) miR-199a expression was measured by RT-qPCR in 50 pairs of OC and matched adjacent non-tumor tissues. **P<0.01 vs. adjacent tissues. (B) miR-199a-3p expression was measured in 50 peripheral blood samples from patients with OC and 50 peripheral blood samples from health donors by RT-qPCR. **P<0.01 vs. normal group. (C) miR-15a-3p expression was detected in three ovarian cancer cell lines (TOV112D, OV90 and SKOV-3) and the normal cervical epithelial IOSE80 cells. Data are presented as the mean ± standard deviation (n=3) of one representative experiment. **P<0.01 vs. IOSE80 cells. miR, microRNA; OC, ovarian cancer; RT-qPCR, reverse transcription-quantitative PCR.